Mutational analysis and coagulation factor VIII sequence in a colt with hemophila A by
نویسندگان
چکیده
.......................................................................................................................................... ii Acknowledgements ........................................................................................................................ iii List of tables .....................................................................................................................................v List of figures ................................................................................................................................. vi List of abbreviations ...................................................................................................................... vi Chapter I: Literature review ............................................................................................................1 Section 1: Coagulation ........................................................................................... 1 Section 2: Inherited coagulopathies in the horse ................................................... 11 Section 3: Coagulopathies associated with coagulation FVIII deficiency .............. 17 Section 4: DNA and genetic mutations ................................................................. 29 Section 5: Justification of the project ................................................................... 33 Chapter 2: Mutational analysis and coagulation factor VIII sequence in a colt with hemophilia A ....................................................................................................... 36 Section 1: Case presentation ................................................................................ 36 Section 2: Materials and methods ......................................................................... 39 Section 3: Results ................................................................................................ 44 Chapter 3: Discussion and conclusions ........................................................................... 68 References ......................................................................................................................................74
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